Obese horses with insulin resistance are often also afflicted with laminitis. Horses with these symptoms are given the diagnosis equine metabolic syndrome (EMS). Signs of insulin resistance are excessive accumulation of adipose tissue on the neck, around the withers and on the dorsal area of the hindquarters. Insulin resistance means that the function of insulin is defective and does not stimulate glucose uptake by the cells in the body in the correct way. This will result in an increased insulin release.

Six cows were subjected to an intravenous glucose tolerance test (GTT) to evaluate the amount of glucose that is needed to stimulate the release of insulin from pancreas. Four of the cows were in early lactation and two were non-lactating and not pregnant. Series of blood-samples were collected to analyze the concentration of insulin and glucose in the blood. The cows were given lower levels of glucose than have been used in earlier glucose tolerance tests. The levels of glucose given were 7,5 mg/kg BW, 15 mg/kg BW, 30 mg/kg BW and 50 mg/kg BW.

This study was made on former agricultural areas that had been planted with spruce or pine, in the county of Västerbotten. The goal of the project was to investigate suspected deficiency of boron in these areas. Several objects have been reported for possible deficiency and some of these have the characteristic symptoms of boron-deficiency. The hypotheses are that 1) Boron deficiency is present at several of the investigated objects. 2) Planting of forest on cultivated postglacial sediments leads to a successive podzolisation with a decreasing content of organic matter in the mineral soil, due to decomposition, and a decreasing pH in the soil, even on locations that have been added lime. To be able to confirm or reject the hypotheses a number of tests were performed.

The purpose of this study is to give an overview about iron fortification from the view of technique and health. Example of a technical aspect is different iron compounds which are used for fortification like ferrous sulfate, ferrous fumarate and elemental iron. In the aspect of health the big question is if iron fortification can improve the health in reducing the prevalence of anemia. The study focuses on flour fortification with iron in Egypt and Iran and involves a literature study with scientific articles. Also information from WHO (World Health Organization), FAO (Food and Agriculture Organization) and FFI (Flour Fortification Initiative) are used.Fortification means an intentionally increasing of the content of micronutrient in foods with the aim to improve the food quality and deliver a nutritional benefit to the consumer.

Background: Prediabetes is caused by relative Insulin deficiency and insulin resistance in the body tissue which leads to abnormal blood glucose levels. Prediabetes can over time lead to type 2 diabetes mellitus. To prevent the onset of type 2 diabetes and its complications, it is important to identify early elevated blood glucose levels and thereby prediabetes.Objective: To describe nurses' knowledge and experience regarding the management of patients with prediabetes.Methods: Qualitative descriptive design with individual interviews. Three nurses, three community health nurses and three diabetes nurses were interviewed.Results: The result can be understood from the nurses' experiences of encountering patients with prediabetes. An overarching theme in the analysis was that the nurses are working or aspiring to work preventively.

Alzheimers sjukdom (AD) är den vanligaste formen av demens och kännetecknas av intracellulärt neurofibrillärt trassel (NFT) bestående av proteinet tau och extracellulära plack, uppbyggda av peptiden amyloid beta (A?). En växande skara studier har börjat peka mot att AD är en hjärnspecifik typ av diabetes. Insulinresistens följt av hyperinsulinemi och hyperglykemi är kännetecken för diabetes mellitus typ 2 (DMT2) och har visat sig vara en riskfaktor för AD. Insulin, ett hormon som kontrollerar glukoshomeostasen i perifera nervsystemet (PNS) och är viktigt för minne och inlärning, transporteras över blod-hjärnbarriären i en mättnadsbar transportmekanism och dess koncentration i centrala nervsystemet (CNS) minskar vid DMT2 och AD.

Diabetes mellitus is an endocrine disorder affecting a range of different mammals, including dogs, cats, horses and humans. Worldwide, 347 million people have diabetes, and the disease is an increasing burden on the world?s poorest countries. The disease is characterised by chronic hyperglycaemia and afflicted individuals experience increased thirst, polyuria and weight loss, sometimes despite increased appetite. Diabetes mellitus is either insulin dependent or non-insulin dependent.

Diabetes mellitus (DM) is a relatively common endocrine disease in dogs and is more common in certain breeds than others, e.g. Nordic spitz breeds. Within the Swedish and Norwegian Elkhound population, female dogs are almost exclusively affected. The hypothesis in this study is that Swedish- and Norwegian Elkhounds develop DM during the progesterone phase of estrous (diestrous or pregnancy). Medical records from 51 female dogs of the breeds Swedish and Norwegian Elkhound were studied.

Diabetes Mellitus is one of the most common endocrinologic disorders among dogs. The disorder has a complex background, and successful treatment requires a well-functioning co-operation between pet owners and the veterinarian. The purpose of this study is to investigate the owners? perspective of diabetic treatments offered, and to estimate expected length of survival post-insulin therapy. The research findings are based on a survey mailed to 77 pet owners, whose dogs were diagnosed with diabetes between 1999 and 2003 at the small animal clinic of the Swedish University of Agricultural Sciences. The median survival for the dogs that underwent insulin treatment was 31 months, i.e.

AbstractTrendanalys av rapporterade störningar vid de svenskakärnkraftverkenAnalysis of trends in reported safety-related events atSwedish nuclear power plantsSafdar KargarThis degree project was conducted at the Swedish Radiation Safety Authority (SSM)as part of the bachelors program in Nuclear Engineering at Uppsala University duringthe spring of 2011.The Swedish Radiation Safety Authority (SSM) has developed a Windows baseddatabase called ?ASKEN? during later years. In this database more than 12 000 eventreports are stored sorted in three categories, category 1, 2 and 3. The databasecontains events from the start of Oskarshamn 1 in 1972 till present time.All nuclear power plants in Sweden are obliged to report any deficiency in theirbarriers and/or the defense in depth in obedience to SSMFS 2008:1.When a failure is detected or there is reasonable suspicion of a deficiency, the eventreport should be classified as a deficiency of category -1, 2 or 3 [1].The event reports are logged and archived in the register of SSM. The SSM task forceAnalys av Störningar på elproducerande Kärnkraftverk (the ASK-group), evaluates allincoming event reports and categorizes them according to established criteria.The aim of the project is to study and analyze the event reports in the database andidentity interesting observations and trends which should be investigated morethoroughly by deeper analysis to establish any positive or negative trends of reportedevents. .

Dräktighetstoxikos är en metabolisk sjukdom som framför allt drabbar högdräktiga tackor med fler än ett foster. Sjukdomen karakteriseras av flera ämnesomsättningsrubbningar men orsak och patogenes till sjukdomen är fortfarande inte helt känd. Det är därför svårt att förebygga sjukdomen och behandla tackorna på rätt sätt, vilket gör att många tackor som drabbas av dräktighetstoxikos inte överlever utan dör efter några dagar med symptom. Syftet med litteraturstudien var att belysa de två mest omtalade teorierna, undernäring och bristfälligt energiutnyttjande, som orsaker till varför dräktighetstoxikos uppkommer. Den första bygger på att sjukdomen orsakas av undernäring hos tackorna och karakteriseras av hypoglykemi och hyperketonemi.

Fertility is of central interest in the dairy production but has during the last decades declined. Increased milk yield has resulted in high pressure on the metabolism of the dairy cows that are supposed to manage the transition from dry cows to lactating cows within a few weeks around the parturition. Much indicate that metabolism and fertility are closely linked, with insulin playing a substantial part. There are many studies suggesting that the main part of gestation loss can be found during the early embryo development, a period which can be studied in vitro. The aim of this study was to test the effect of insulin during maturation in vitro and to evaluate two different fluorescent stainings on oocytes and embryos; a nuclear stain and a staining of apoptotic cells through the terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL)-method. Bovine cumulus-oocyte-complexes (n=991) were aspirated from abattoir-derived ovaries.

Både typ 2-diabetes och D-vitamin brist ökar hos världens befolkning och ett samband mellan förekomsten av dem båda har setts i olika studier. Typ 2-diabetes ger en minskad känslighet för insulin samt en ökad resistens där cellerna svarar dåligt på insulinet. Med tiden tröttas de insulinproducerande ?-cellerna ut och sekretionen avtar. Vitamin D bildas ur 7-dehydrokolesterol i hudens celler vid UV-ljusbestrålning eller tas upp från födan.

AbstractTrendanalys av rapporterade störningar vid de svenskakärnkraftverkenAnalysis of trends in reported safety-related events atSwedish nuclear power plantsSafdar KargarThis degree project was conducted at the Swedish Radiation Safety Authority (SSM)as part of the bachelors program in Nuclear Engineering at Uppsala University duringthe spring of 2011.The Swedish Radiation Safety Authority (SSM) has developed a Windows baseddatabase called ?ASKEN? during later years. In this database more than 12 000 eventreports are stored sorted in three categories, category 1, 2 and 3. The databasecontains events from the start of Oskarshamn 1 in 1972 till present time.All nuclear power plants in Sweden are obliged to report any deficiency in theirbarriers and/or the defense in depth in obedience to SSMFS 2008:1.When a failure is detected or there is reasonable suspicion of a deficiency, the eventreport should be classified as a deficiency of category -1, 2 or 3 [1].The event reports are logged and archived in the register of SSM. The SSM task forceAnalys av Störningar på elproducerande Kärnkraftverk (the ASK-group), evaluates allincoming event reports and categorizes them according to established criteria.The aim of the project is to study and analyze the event reports in the database andidentity interesting observations and trends which should be investigated morethoroughly by deeper analysis to establish any positive or negative trends of reportedevents. .

Abstract: Typ-1 diabetes eller så kallad insulinberoende diabetes, drabbar vissa barn och tonåringar. De tvingas leva hela sina liv med att injicera insulin i sin kropp, eftersom deras egen kropp har slutat tillverka insulin på egen hand. Insulinpennan är typ-1 diabetikers medicinska redskap som de måste ha tillhands vid varje måltid.Syftet med denna studie är att utveckla och ta fram ett exempel på hur ett grafiskt gränssnitt med Mp3-spelare bör se ut i en insulindoserare som riktar sig till tonåringar. För att utreda hur gränssnitt ska utformas har kvalitativa intervjufrågor ställts till produktutvecklare, diabetessjuksköterskor och tonåringar. Vidare har också analyser gjorts på befintliga insulinpennor och Mp3-spelare.Resultatet av studien är en prototyp av en insulindoserare som simuleras i Shockwave.